The purpose of the Meds75+ database of medication for older persons is to support the clinical decision-making on the pharmacotherapy of patients over 75 years of age and to improve medication safety in primary health care. The database contains classification and recommendation for almost 500 substance or their combination when used in older persons.
The Meds75+ database is maintained by the Finnish Medicines Agency, Fimea. The database is available free of charge on Fimea’s website.
Content of the database
Like in other health care databases, the medicinal substances are classified into categories A, B, C and D. The category indicates how suitable the medicinal substance is for persons over 75 years of age. The categories are based on a multidisciplinary clinical consensus.
- A (green): Suitable for the older persons. The medicinal substance can be used as in younger patients. Changes due to aging do not affect the dose or frequency of administration, and the adverse reaction profile is not different from that of younger patients.
- B (grey): There is little research evidence, practical experience or efficacy in older persons.
- C (yellow): Suitable for older persons, with specific cautions. The medicinal substance can be used by older persons, but the dose might either have to be reduced, or the frequency of administration decreased due to mild or moderate renal insufficiency or a significant risk of interactions or adverse reactions.
- D (red): Avoid use in older persons. Use is possible only in exceptional cases or on a one-off basis. Changes due to aging predispose older persons to adverse or dangerous reactions to the drug, The risk of adverse reactions typically exceeds the benefits.
The legend for each pharmaceutical substance contains information on the effects and dosing of the substance and the most typical adverse reactions and interactions. The legend does not contain indications or contraindications.
Commonly used criteria on inappropriate medication for older persons (Beers, STOPP/START, Laroche) were taken into account in composing the database.
Using the database in health care
The database is primarily intended for physicians and other health care professionals. It must be borne in mind that individual cases might require the use of category D medicinal products. The pharmacotherapy must be started, changed or discontinued under the supervision of a physician.
Meds75+ (zip package)
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